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Former House star Amber Tamblyn is checking in to Two and a Half Men.

The actress will appear on at least five episodes of Season 11 as Jenny, the 21-year old long lost daughter of Charlie Sheen’s Charlie, who moves to Los Angeles to try her hand at acting and who ends up residing with Walden (Ashton Kutcher) and Alan (Jon Cryer).

Oh, and the character will be a lesbian.

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“She’s somewhat of a chip off the old block,” says executive producer Chuck Lorre. “She’s having a good time and doesn’t care about the destruction left behind her. Decadence from the other side felt long overdue.”

Tamblyn will essentially replace Angus T. Jones, who will scarcely appear again on the sitcom. She will debut on the September 26 premiere and may end up as a series regular.