Dalton Prager, one half of a couple many have compared to the fictional couple at the center of Fault in Our Stars, passed away on Saturday in a St. Louis hospital.
He was 25 years old.
Dalton and his wife, 26-year old Katie, were both born with cystic fibrosis.
This is a progressive genetic disease that mainly primarily the lungs; those who suffer from the illness have an average life expectancy of around 40 years.
Despite their afflictions, Dalton and Katie got married in July of 2011, garnering headlines at the time because their situation mirrored that of the main characters in Fault in Our Stars, a John Green novel that centered on star-crossed cancer patients who fell in love.
It was turned into a movie in 2014.
Katie - who checked into hospice care earlier this month at the couple's Kentucky home (nearly 400 miles miles away from her husband) - confirmed Dalton's death on Facebook.
(The soulmates had met in 2009 on that social media website and instantly formed a friendship that blossomed into love.)
"My angel, my best friend, the love of my life, my husband went to be with the Lord our God today," Katie wrote.
"Dalton fought a long hard battle with Cystic Fibrosis. He was a courageous fighter and 'give up' wasn't in his vocabulary."
After meeting each other, Katie and Dalton both sought life-prolonging lung transplants.
"We wanted to keep living, we wanted to keep traveling, we wanted to just keep being the married couple that we always wanted," Katie tells People Magazine.
Following battles with various ailments that landed them each in the hospital at different times, Dalton underwent his transplant in 2014; Katie got hers a year later.
However, the two never fully recovered from their procedures.
Their difficulty in rebounding forced Katie and Dalton to go their separate ways in order to be close to family members that could assist them with their medical needs.
But, with the end near, Dalton’s family made arrangements for their loved one to be transferred to the University of Kentucky Medical Center in Lexington, approximately an hour from the couple's home.
In the days prior to his passing, though, Dalton was not well enough to make the trip.
The husband and wife had last seen each other briefly, for just a few minutes, in Katie's Kentucky hospital room on their anniversary in July.
"Today … September 17, 2016 at 12:56 Dalton Lee Prager joined his sister, Samantha, and grandfather, Larry, in Heaven," Dalton's mother, Renee Prager, wrote on the couple's Facebook page. "
You may Breathe Easy now my son. You are my true hero. Love Forever, Mom."
Those close to Dalton and Katie have set up YouCaring.com accounts to cover end-of-life and funeral expenses for each.
"The past week has been very emotional and decisions have been made that aren't meant to be made by someone in their 20s with their whole life ahead of them," Katie shared on September 2, after choosing to leave the hospital and enter a hospice program.
"There are too many things going on in my body to be able to fix everything. Things appear to be going downhill faster than I thought they would. My hospice nurse is coming out today to get everything set up.
"I won't have to go back to the hospital or get anymore IVs. I get to spend the rest of my time surrounded by people and things that make me happy.
"Please don't take this as a sign of me giving up. It's the last thing I want people to remember of me.
"God bless you all and thank you for going on this journey with me! Love, Katie."
Amazing. God bless both of these people.