Alex Cross Trailer: Matthew Fox vs. Tyler Perry!

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Matthew Fox, whose apparent mean streak has been well-documented of late, transforms into a serial killing cage fighter in the trailer for Alex Cross.

The 45-year-old actor radically transforms his body into 100 percent muscle for the film, in which his character goes up against ... Tyler Perry.

Yup, the actor-director plays the titular hero, based on author James Patterson's famed detective and played by Morgan Freeman in Kiss the Girls and Along Came a Spider.

Big shoes to fill for Perry. Check out the trailer:

­The thriller, directed by The Fast and the Furious' Rob Cohen, finds Cross investigating murders committed by ex-military hitman, Matthew "The Butcher" Sullivan (Fox).

Sullivan eventually targets Alex's wife, obviously.