For the big O, it's time to go.
During tomorrow's broadcast, Oprah Winfrey will officially announce the end of her network television talk show. Its final airdate will be September 9, 2011.
"Tomorrow, Oprah will announce live on The Oprah Winfrey Show that she has decided to end what is arguably one of the most popular, influential and enduring programs in television history," Tim Bennett, the President of Harpo productions, wrote in a statement.
Bennett sent out the letter in order to prevent affiliates from being shocked at the announcement.
"Before she speaks to her loyal viewers, we wanted to share her decision first with you - our valued partners for more than two decades," he wrote.
Of course, Winfrey is unlikely to leave television altogether.
It's been rumored for weeks that the icon will take the gabfest to her previously announced cable channel, the Oprah Winfrey Network (OWN), which also launches in 2011.
Will you miss her on network TV?