Earlier today, Joan Rivers passed away after complications from a surgical procedure caused her to be placed in a medically-induced coma last week.
In a way, it was fitting that we learned of Joan's condition the same day that we found out Angelina Jolie and Brad Pitt got married.
Joan spent much of her career deflating the egos of A-list stars, and she likely would've gotten kick out of the fact that her last act involved upstaging the world's most famous couple.
Sadly, we'll never get to hear Joan's biting takedown of Angie's wedding dress.
The loss of her talent will leave a void in the comedy world that won't be easy to fill, as even at the age of 81, Rivers frequently made headlines for her often controversial - and always witty - insights on celebrities, fashion, and world events.
It's hard to pin down the funniest and most shocking moments from her more than five decades in the spotlight, but we've compiled some of her most indispensable feuds, one-liners, and wisecracks in the gallery above.
Though in the past year Joan may have been best known for her feud with Kim Kardashian and her comments on the Israel-Gaza conflict, for many she'll be remembered as a trailblazer in the world of entertainment - breaking new ground and influencing female comics from Roseanne to Sarah Silverman.
While the mention of the name Joan Rivers might always bring to mind scathing, impeccably-timed insults, those who knew her best say that she embodied bravery and compassion and was always quick with a kind word.
Rest in peace, Joan.