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Ellen DeGeneres is famous for pranking guests, but when Dennis Quaid comes on, it’s a little different. He teams up with her and they prank strangers!

This week, she had Dennis fake a series of health issues – some of which aren’t even possible – just to have fun with a nurse on set. Safe to say it worked.

Dennis Quaid Prank on Ellen

From lung problems to shrinking, the actor had the unassuming nurse run through a variety of utterly ridiculous tests – with Ellen’s guidance of course.

The poor nurse didn’t even realize what was going on when the reveal finally came. Gotta hand it to her for remaining professional throughout all of that.

This is not the first time Ellen and Dennis have teamed up for some hidden camera hijinks. Watch more of their hilarious moments in recent years below: