Man Handler: Did Chelsea Dump 50 Cent?

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Chelsea Handler is getting quite the reputation these days.

First she tells off Angelina Jolie ... then she strikes up a romance with 50 Cent, only to dump him just before the holidays, leaving the rapper "heartbroken."

Chelsea Handler Playboy Cover

That's according to Us Weekly, which adds that to win her back, 50 pulled out all the stops and "spent Christmas sending her gifts, but she sent them back."

"She put a note on one that said, 'I can buy my own gifts.'"

BANG BANG: Chelsea supposedly shot 50 down hard!

Cent, who was first spotted canoodling with the Chelsea Lately host in October, denied they dated in an interview this week. But perhaps there's more to it?

A reconciliation looks like the last thing on her mind, in any case.

According to an eyewitness, Handler had already set her sights on Uma Thurman's ex, hotelier Andre Balazs, 54. "They snuck kisses" last week, reports say.

Perhaps 50 will channel his pain into a moving new rap ballad.

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I don't think it was ever anything serious, whatever they had. He shouldn't trip that she's not interested in him, just having fun but some people don't take casual relationships well me included.

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Fif should 4get about her 4 there are so many fishes in the water.