And now she's spilling the beans on the person who managed to make more headlines last year than the Kardashians: Caitlyn Jenner.
Because what's a little sh*t talk among family members?
Khloe says she felt betrayed by Caitlyn because she wasn't forthcoming with the family about her transition before it happened.
"All these tabloids are coming out ... we're like 'we could ask the source. You're our dad, we'll ask you,'" said said.
And they did. But Caitlyn (then Bruce) kept telling them the rumors weren't true.
In fact, she says E! producers knew before the family did - and that stung.
"Something happened where we were at a meeting with E! for something and they mentioned that Bruce was having a TV show about transitioning or something," she said. That's the first we heard of it."
That's a pretty big bomb to drop on a business meeting with fam.
"We felt so like 'what the fuck? We've been asking you and why do business people know?'" she explained.
"I never want someone to feel like they have one-up on our family. We are a family. We've never turned our backs on each other yet with all the clusterf**ks of sh*t that's happened in our lives, why would we now?"
Clusterf**cks of sh*t? What a brilliant way to describe the lives of the Kardashenners! Hey, she said it.
Nevertheless, she was justifiably pissed.
Khloe recalled that at first, he would only want to talk to them about transitioning when the cameras were rolling.
"Maybe he felt like we couldn't get as upset or whatever."
She said all she wanted was her dad to be honest.
"I don't give a fuck what you want to do - just stop lying to us about things," she said. "Each sister had a different story because he couldn't keep up."
"We didn't know when he was going to start fully dressing as Caitlyn," she added.
In Caitlyn's defense, coming out to your family as trans is probably one of the most difficult things a parent would ever have to do.
And there isn't exactly a handbook on how to do it.
Plus, let's be honest, ANYONE would be scared sh*tless around that family.