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A defiant Dr. Mehmet Oz addressed a group of Columbia University doctors who are calling for him to resign while taping his namesake show on Tuesday.

A preview for The Dr. Oz Show slated to air on Thursday was released by show producers on Tuesday night, and the TV doctor makes zero apologies.

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"This month, we celebrate my one thousandth show," Oz, 54, says in the preview.

"I know I’ve irritated some potential allies in our quest to make America healthy.

"No matter our disagreements, freedom of speech is the most fundamental right we have as Americans. And these 10 doctors are trying to silence that right."

"So I vow to you right here and right now: we will not be silenced, we will not give in."

His critics wrote a letter to Columbia challenging whether Oz, a cardiothoracic surgeon who holds a vice chair spot at the school, should be a faculty member.

Their list of complaints about him is not short. The group’s letter reads:

"We are surprised and dismayed that Columbia University’s College of Physicians and Surgeons would permit Dr. Mehmet Oz to occupy a faculty appointment."

"Let alone a senior administrative position in the Department of Surgery."

"As described here and here, as well as in other publications, Dr. Oz has repeatedly shown disdain for science and for evidence-based medicine."

Furthermore, the group of critics alleges, Dr. Oz exhibits "baseless and relentless opposition to the genetic engineering of food crops."

"Worst of all, he has manifested an egregious lack of integrity by promoting quack treatments and cures in the interest of personal financial gain."

Ouch. A spokesperson for the Dr. Oz Show told CNN that two thirds of the episode this Thursday will be devoted to rebutting these doctors’ claims.

Stay tuned.