After the prosecution rested in the Casey Anthony trial, the judge denied the defense's motion for acquittal on the Florida woman's murder charge.
Judge Belvin Perry said the state presented "substantial, competent evidence" that Anthony's daughter Caylee was slain and she was responsible.
The defense now must proceed with its case on Thursday.
Anthony faces three charges, including first-degree premeditated murder. She had no reaction in the Orlando court when the motion was denied.
Her attorney, Cheney Mason, had argued that prosecutors failed to present evidence that a murder had even occurred, premeditated or otherwise.
"There has been no evidence of premeditation," the lawyer said. "There has been a stacking of inferences. A stacking of speculation. No evidence."