Just weeks after Grey’s Anatomy returned with new episodes, sources are saying Katherine Heigl is itching to bolt and hang up her scrubs. Again.

This is not the first time this rumor has circulated. Nor will it be the last. Heigl is said to be dreaming of bigger and better things.

“She’s working really long hours and is ready to move on,” a source close to the actress told MSNBC.

Fifteen months ago, Heigl renegotiated her Grey’s Anatomy contract. The net result was that the negotiations went public and she got the raise she wanted from the show, but questions about her status have lingered.

ZZZZ: Being extremely hot and full of one’s self is hard work!

Compounding the issue is the fact that Heigl has already had significant big-screen success with her leading roles in Knocked Up and 27 Dresses. She’s slated to star with Gerard Butler in The Ugly Truth next.

“She is smart. She saw what can happen with somebody like Jennifer Aniston, who was crazy successful on TV, but can’t seem to carry a film, and she tested the waters early,” said a movie industry source.

Even so, Katherine Heigl might be locked into Grey’s Anatomy a bit longer. “I don’t think she’ll be able to get out of it,” the source said of her contract.

Ghost Whisperer star Jennifer Love Hewitt and Grey’s Anatomy star Patrick Dempsey were recently voted the sexiest stars on TV by TV Guide.

Hard to argue with that logic. The respective hotties will appear on two alternative covers of the TV magazine’s “Sexiest Stars” issue.

In honor of the (well-deserved, sexy) honors earned by Jennifer Love Hewitt and Patrick Dempsey, here is a very sexy photo of each. Enjoy …

J. Love and Patrick Dempsey: The sexiest stars on TV.

All we have to say about these pics is that McDreamy is living up to his McNickname, and man, all those ghosts Jennifer Love Hewitt whispers to on the CBS TV show she apparently stars on are pretty damn lucky.

McDreamy is no McSteamy, Patrick Dempsey admits.

“I’m not Eric Dane — McSteamy is in perfect shape” the Grey’s Anatomy star tells the new issue of Parade Magazine. “I definitely have pec envy.”

“There’s a lot of pressure being a man in this town.”

He says his wife of eight years, Jillian, keeps him grounded.

“She always says in the morning, ‘They should see you now!’” jokes Dempsey, who adds that fame “gets very heady … you’ve got to be very careful.

“I think I’ve been managing that well. This is a great opportunity now to really define the next part of my life. I just want to do it right.”

Defining the life of Patrick Dempsey these days at home? His daughter Tallulah, 6, and his one-year-old twins, Darby and Sullivan.

“It’s like a slapstick routine watching these drunk little men run around because they’re so wobbly,” he says. “When you see something happen that they couldn’t do the day before, it’s really heartwarming.”

As for what happens tonight with Meredith and Derek? That you’ll have to wait and see, although Dempsey says he’s “excited” for the couple to finally move forward and grow together.

Patrick and the rest of the Grey’s Anatomy cast return at 9 p.m. on ABC. How well do you know the hit medical drama? Follow this link for an exclusive Grey’s Anatomy quiz!

Just call him Dr. McDreamy … on Grey’s Anatomy and in real life!

Patrick Dempsey unveiled a cancer center in his name at the Central Maine Medical Center in his hometown of Lewiston, Maine, on Monday.

The Patrick Dempsey Center for Cancer Hope & Healing, which opens March 31, will offer education and support for cancer patients and their families.

The handsome Grey’s Anatomy star, 42, says he was inspired after his mother successfully overcame ovarian cancer at the hospital.

“For a family to get a cancer diagnosis is devastating, and all the information out there can be overwhelming,” Patrick Dempsey said.

“A lot of the Web sites I went to just didn’t have enough information.”

Patrick provided a seed grant for the center, will also take part in the center’s public education campaign about cancer prevention and detection.

His sister, Mary, a hospital employee, will run the center.

Dempsey has been married to his wife, Jillian Dempsey, for eight years. They have twins, Darby and Sullivan, 1, and a daughter, Tallulah, 6.

With all the scandal we write about on The Hollywood Gossip, it’s always nice to see that some celebrities are grounded and giving back to their community.

A naked, writhing, sweaty Marisa Tomei engaged in feverish, doggy-style sex might sound terrific to a lot of you guys reading this.

Well, yeah… and if it weren’t for the hulking, naked Philip Seymour Hoffman going to town on her, we might share that sentiment.

This is why some sites have called the raunchy, vigorous Marisa Tomei nude scene - from “Before the Devil Knows You’re Dead” - the best sex scene of its naked kind in 2007, while others have deemed the same scene the year’s worst.

Good: Marisa Tomei nude. Bad: Philip Seymour Hoffman nude on top of her.

It’s like a metaphor for life. Every Marisa Tomei naked scene has its pudgy, nude Philip Seymour Hoffman counterpart. Yin and yang. Okay, moving on.

Papermag’s Cinemaniac compiled his list of the Top 10 Worst Nude Scenes of All Time, inspired by “Before the Devil Knows You’re Dead.”

Here are the rest of the scenes and celebrities making the list, such as Grey’s Anatomy star Patrick Dempsey and some actually good actresses…

Read the rest of this entry �

We know. It’s extremely difficult to compete with George Clooney in this category, even if your TV character gave birth to the term McDreamy.

But Patrick Dempsey pulls it off.

Not just because he’s a handsome fellow, either. Patrick Dempsey is one of the most laid-back celebrities out there, unmoved by his own fame.

He and his wife, Jillian Dempsey (pictured), have been married since 1999 and have three children. That’s an eternity in Hollywood, or anywhere these days!

For these reason, the Grey’s Anatomy / Enchanted star and family man was the dreamiest star on the red carpet last night, in our opinion …

No, he’s not angling for Patrick Dempsey’s role on Grey’s Anatomy. But the husband of Ellen Pompeo can’t help but gush about married life.

At Paris Fashion Week Monday, the actress and her longtime partner / spouse of two months were clearly still on cloud nine over their recent nuptials.

“We’re blessed,” the 38-year-old Grey’s Anatomy star said. She and Chris Ivery tied the knot in New York City on her birthday in November.

Chris Ivery is the McDreamy of Ellen Pompeo in real life.

But does Ellen Pompeo think that her TV alter ego, Meredith Grey, will ever find similar happiness with Derek “McDreamy” Shepherd?

“Who can say?” she sighed at Italian designer Giorgio Armani’s Monday fashion show. “We’re not working because of the writers’ strike.”

Chris Ivery, a music producer, piped in on cue: “I am the real McDreamy!”

Also on hand for Armani’s show in the City of Lights were Hilary Swank, Dita von Teese and the legendary Sophia Loren.

Lance Armstrong who? Grey’s Anatomy star Patrick Dempsey makes like the cycling champ and rides to glory (or at least to the store) in Los Angeles this week.

The man behind McDreamy is a major auto racing and cycling enthusiast.

The writers’ strike in Hollywood has Patrick Dempsey temporarily out of work, but on the bright side, that means more time with the bike - and the kids. He also has a big, hit movie out right now with Enchanted. Life is good for this doc.

Life will also good for you, readers, if you follow the link and check out The Hollywood Gossip’s gallery of Patrick Dempsey photos. Hotness alert!

Hmm… auditioning for Dancing with the Stars‘ next season? Probably not. But “Enchanted” costars Amy Adams and Patrick Dempsey certainly have got some skills!

Below, the Grey’s Anatomy actor and the cute redhead teach the audience the proper steps to a Viennese Waltz during taping of TRL Monday in New York.

Patrick Dempsey: Always McDreamy … even on the dance floor.

Patrick is certainly enjoying a career revival, with Grey’s Anatomy now in its fourth season, Enchanted in theaters now, and a new romantic comedy, Made of Honor, due out in 2008. One can never get enough Dempsey in our opinion!

Love and happiness (and cut-off camo shorts) are in the air, folks. A week after quietly getting married in New York City, newlyweds Ellen Pompeo and Chris Ivery went out for sushi in Los Angeles on Thursday, November 15.

Ellen Pompeo and Chris Ivery: Celebrating their one-week anniversary!

The Grey’s Anatomy star has been dating Chris Ivery, a music producer, for a long time. Both are Boston-area natives. They got engaged just as quietly on Pompeo’s birthday almost exactly one year ago, then tied the knot last Friday on the eve of the actress’ 38th birthday. N.Y. City Mayor Michael Bloomberg was their witness.

Congratulations again to the happy couple!