It was Thanksgiving in Quahog on Family Guy Season 13 Episode 5, though Brian and Peter were in more of a hungry mood than a gracious mood. They got drunk and devoured the entire turkey the night before the big meal.
Lois, naturally, was displeased with this development. She sent her husband and dog away to track down a replacement.
However, every supermarket within 60-mile radius was sold out.
They do finally track down a turkey far outside of town, with Peter trying to dunk it in a basketball court. So Brian takes control of the bird and tells Peter to drive home. Except he can’t operate a Hybrid and they crash into a lake.
With Peter still not home, Stewie talks Chris into stepping up as man of the house. He tries to play host and ends up giving the greatest Thanksgiving speech in recorded history (“Yesterday I’m microwaving a cat and today I’m giving a speech!”).