Brian Williams, Katie Couric and Diane Sawyer are teaming up to Stand Up to Cancer for the second time in three years.
The charitable telecast, which raised $100 million in the fall of 2008, will air on September 10.
The inaugural broadcast's lineup featured such A-list stars as Beyonce, Miley Cyrus, Jennifer Aniston, Ellen DeGeneres and Jennifer Garner.
"Stand Up To Cancer is a populist movement," said Couric. "People of all ages are getting involved... Not only people who have cancer or who are dealing with it, but young people who want a cancer-free world in their future – we really think that's finally attainable."
Added Sawyer: "The broadcast is a way of saying, 'Together, we can do this.' And yes, we're losing one person every minute, but 11 million survivors are out there; living proof that this can be done."
Tune in September 10 and help raise money for this important cause.