Our heart goes out to Katie Holmes, following today's tragic family news.

The actress' brother-in-law has passed away.

Joseph Jeffrey Fretti - the 48-year-old husband of Holmes' older sister Tamera - died of heart failure Sunday.

Reportedly, Fretti was found dead by a family friend. His body was discovered in the Sarasota home of his mom, as he had taken his two young kids to visit their 76-year-old grandmother.

Fretti was the owner of a funeral home in Holmes' hometown of Toledo, Ohio.