Grey's Anatomy Co-Star: Katherine Heigl, T.R. Knight No Longer Fans of Show, Expect to Be Cut Loose Soon

Grey's Anatomy spoiler alert! After months of rumors that stars Katherine Heigl and T.R. Knight may be leaving the show, their co-star James Pickens, Jr., a.k.a. The Chief, has added fuel to the fire by sort of confirming they are:

"Yes, she is," he said when asked by Us Weekly if Heigl will exit the show that made them famous. "Wherever Katherine goes, I wish her nothing but the best."

As for Knight, Pickens said, "He's going too."

The network and studio say they cannot confirm anything, and Katherine Heigl's and T.R. Knight's personal reps have declined to comment on the subject.

However, an ABC source says, "There's no way [James Pickens] could know that, because nothing has been decided yet. Nothing has been written and [Heigl and Knight] are still working out what will happen next season with the network."

T.R. Knight and Katherine Heigl want out of Grey's Anatomy.

According to inside sources who work closely with Grey's Anatomy, it is likely that Heigl and T.R. Knight will make an exit at the end of the current fifth season.

Both have asked to leave. However, ABC needs to sign off on letting them out of their contracts, which extend six years, and that hasn't been done.

So why did Pickens say they are leaving?

"I don't think James meant to say what he did," one insider said. "I think he was thrown by the line of questioning and didn't realize what he was saying."