Grey's Anatomy, Lost, The OC Bid Farewell to Key Characters

It was a heartbreaking year in Hollywood. And, no, we're not just referring to recent troubles for that drug addicted Miss USA, Tara Conner.

On the small screen, main characters from some of our favorite shows were sent to the great big DVR in the sky.

Here's a recap of the most memorable:

• As if the trials and tribulations of Meredith and McDreamy were not enough, Grey's Anatomy made us fall in love with Denny Duquette. And then killed him off in the season finale. George Clooney didn't love his pig as much as we loved Denny.

• On Lost, meanwhile, fans were just getting to know Mr. Eko. Unfortunately, the smoke monster on the island was, as well. And the mysterious wanna-be priest didn't stand a chance against it.

• We can't say we felt the same sort of loss when The OC cut ties with Marissa, played emaciatedly Mischa Barton, however. That annoying drag on Ryan worn out her welcome months earlier.

Good riddance to her. But best of luck to former real-life couple, Rachel Bilson and Adam Brody!